Which medication increases neutrophil counts in neutropenia?

Which medication increases neutrophil counts in neutropenia?

• A. Enoxaparin
• B. Warfarin
• C. Filgrastim
• D. Clopidogrel

Answer: (C)

Raising neutrophil counts in neutropenia is best achieved with a growth factor that specifically stimulates the neutrophil lineage. Filgrastim is a recombinant granulocyte colony-stimulating factor (G-CSF) that acts on hematopoietic progenitor cells in the bone marrow to proliferate and differentiate into neutrophils, and it also helps neutrophils survive longer. By accelerating neutrophil production and release, it increases circulating neutrophil counts and reduces the risk and duration of neutropenia-related infections. The other drugs listed are anticoagulants or antiplatelets; they affect clotting pathways or platelet function, not neutrophil production, so they don’t raise neutrophil counts.

Raising neutrophil counts in neutropenia is best achieved with a growth factor that specifically stimulates the neutrophil lineage. Filgrastim is a recombinant granulocyte colony-stimulating factor (G-CSF) that acts on hematopoietic progenitor cells in the bone marrow to proliferate and differentiate into neutrophils, and it also helps neutrophils survive longer. By accelerating neutrophil production and release, it increases circulating neutrophil counts and reduces the risk and duration of neutropenia-related infections. The other drugs listed are anticoagulants or antiplatelets; they affect clotting pathways or platelet function, not neutrophil production, so they don’t raise neutrophil counts.